Blood metabolic profiling associated with a short-term intensive training period in elite male water polo athletes: an exploratory metabolomics study

Key Points

• This study aims to explore the metabolic changes in elite male water polo athletes following a short-term intensive training regimen.
• Utilized non-targeted LC‒MS/MS for serum metabolome analysis.
• Monitored metabolic adaptations during a short-term intensive training period.
• Assessed changes in amino acid and lipid metabolism.
• Observed significant changes in the serum metabolome post-training.
• Identified specific adjustments in amino acid and lipid metabolism associated with intensive training.
• Provided insights that could inform fitness and performance optimization strategies.