Stress, Depression, and Quality of Life in Cervical Cancer Patients and Sexual Dysfunction in Cervical Cancer Survivors: A Cross-sectional Comparative Study

Abstract Background: with the increasing prevalence of cervical cancer and the availability of better treatment options, there are patient and survivors who are in need of mental health care. Objectives: This study aimed to assess the level of stress, prevalence of depression, and quality of life (QOL) in cervical cancer patients and assess sexual dysfunction among cervical cancer survivors compared to healthy controls. Materials and Methods: This was a cross-sectional survey conducted at the Department of Psychiatry and Department of Oncology, Pramukhswami Medical College, Karamsad, Gujarat. The study enrolled 60 patients (39 undergoing treatment for cervical cancer, 21 survivors of cervical cancer) and 52 controls. The following data were collected from participants: demographic and treatment details, VAS to assess stress levels, HAM-D 17 scale for depression severity, QOL scale, and female sexual function index-6 to assess sexual dysfunction. Statistical analyses included descriptive statistics, the Shapiro–Wilk test, nonparametric tests, and comparisons using Mann–Whitney U and Fisher’s exact tests. Results: The treatment group had significantly higher stress levels, prevalence of depression (59%), and poorer QOL compared to controls. Survivors had a significantly higher prevalence of depression (9.5%) compared to controls but similar stress levels and QOL. Sexual dysfunction was prevalent among 62.5% of survivors compared to 23.1% of controls. Conclusions: Cervical cancer patients undergoing treatment experience higher levels of stress, depression, and lower QOL compared to survivors and healthy controls. Cancer survivors have a significantly higher prevalence of sexual dysfunction compared to healthy controls. Comprehensive care strategies addressing both physical and psychological aspects are crucial for their recovery and well-being. Strengths and Limitations: Demographic consistency strengthens the validity of the psychological and QOL comparisons made between study groups. Sample collected from a single center-hospital population, and small sample size and homogenous demographic profile may limit the generalizability of the study results. Use of self-report measures, cross-sectional study method, and lack of longitudinal data may have introduced reporting bias and do not allow for assessing causality.