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March 21, 2026TransfusionOpen Access

Management of neonatal massive hemorrhage: A narrative review

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Authors

CCCheryl S. L. ChooiMSMary Claire SimmondsLFLaura Fisher

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Overview

Narrative review addresses management strategies for neonatal massive hemorrhage, highlighting necessary clinical considerations.

Key Points

  • This review aims to analyze the current management practices and physiological challenges associated with neonatal massive hemorrhage.
  • Conducted a narrative review of existing literature on neonatal massive hemorrhage.
  • Evaluated current transfusion guidelines and recommendations.
  • Discussed physiological differences in coagulation and blood volume in neonates.
  • Examined the role of viscoelastic testing in transfusion management.
  • Reported a 25% incidence of bleeding in neonates, with 11% being severe.
  • Identified significant limitations in existing guidelines adapted from adult practices.
  • Emphasized the need for a standardized approach to transfusion thresholds.
  • Highlighted that viscoelastic testing may reduce the risk of volume overload.

Cite This Study

Chooi et al. (2026) studied this question.

synapsesocial.com/papers/69be35a96e48c4981c67400chttps://doi.org/10.1111/trf.70186
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