Association of radiomic features of skeletal muscle on CT images with muscle function and physical performance in older men

Megan Hetherington-Rauth; Tyler A Mansfield; Leon Lenchik; A. R. Weaver; Deborah M. Kado; Nancy E Lane; Eric S Orwoll; Peggy M Cawthon

doi:10.1093/ageing/afag057

March 1, 2026Age and Ageing

Association of radiomic features of skeletal muscle on CT images with muscle function and physical performance in older men

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Key Points

To investigate how CT-derived radiomic features of skeletal muscle relate to muscle function and physical performance in older men.
Used CT images to extract radiomic features from the trunk region.
Assessed muscle function through strength and mobility tests.
Evaluated physical performance in older men.
Found significant associations between radiomic features and measures of strength.
Identified links between muscle characteristics and mobility outcomes.
Demonstrated that radiomic features can predict physical performance.

Implication

Radiomic analysis shows association between muscle function and physical performance in older men, suggesting a new assessment method.

Abstract

CT-derived radiomic features in the trunk region may reflect skeletal muscle structural characteristics that independently relate to strength, power and mobility in older men.

Discussion

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Cite This Study

Hetherington-Rauth et al. (2026) studied this question.

synapsesocial.com/papers/69be35f96e48c4981c67497c https://doi.org/10.1093/ageing/afag057

View at Publisher

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Association of radiomic features of skeletal muscle on CT images with muscle function and physical performance in older men

Key Points

Implication

Abstract

Discussion

Cite This Study

Association of radiomic features of skeletal muscle on CT images with muscle function and physical performance in older men

Key Points

Implication

Abstract

Discussion

Cite This Study

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