Morphometric OCT parameters of the lens under accommodative stimulus. Report 1. Assessment of age-related changes

Anterior segment OCT using the CASIA2 system is a highly informative method for assessing morphometric parameters of the crystalline lens under conditions of relative accommodative rest and lens-induced accommodative stress. Under accommodative stress, statistically significant changes included a decrease in the radius of curvature of the anterior and posterior lens surfaces, an increase in lens thickness and nuclear thickness, and a decrease in lens diameter and anterior chamber depth. Analysis of the magnitude of changes induced by accommodative stimulus and their correlation with age demonstrated statistically significant negative associations between age and the radius of curvature of the anterior and posterior lens surfaces, and a positive association with lens thickness.