Demonstrates enhanced skin whitening through tyrosinase inhibition in a specific formulation, suggesting improved skincare benefits.
The 5:1:1 molar ratio of 4-n-butylresorcinol, licochalcone A, and glabridin was the best ratio that could inhibit both tyrosinase activity and melanin content. The formulation containing this ratio combination can enhance the skin whitening efficacy and also can prevent the UV and blue light induced skin pigmentation.
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Zhang et al. (2026) studied this question.
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