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March 21, 2026CardioVascular and Interventional Radiology4 citationsOpen Access

Repeated Genicular Artery Embolization Using Permanent Microspheres for Severe Osteoarthritis and Postsurgical Pain

AAA. Taheri AminAHA. HübnerLAL. Abu-Gharbieh

Key Points

  • The study aims to evaluate the effectiveness of repeated genicular artery embolization using permanent microspheres for pain relief in severe osteoarthritis and post-TKR pain.
  • Introduced repeated genicular artery embolization (ReGAE) using permanent microspheres.
  • Assessed clinical responders at 6 months following the procedure.
  • Evaluated reperfusion of treated vessels and pain relief outcomes.
  • All patients who did not achieve the minimal clinically important difference (MCID) showed reperfusion at 6 months.
  • ReGAE increased the percentage of patients classified as clinical responders.

Abstract

After GAE using permanent microspheres, reperfusion of previously treated vessels was observed at 6 months in all patients failing to achieve MCID. ReGAE increased the proportion of clinical responders, supporting its role as an effective additive treatment strategy in severe OA and post-TKR pain.

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Cite This Study

Amin et al. (2026) studied this question.

synapsesocial.com/papers/69be362d6e48c4981c674e2bhttps://doi.org/10.1007/s00270-026-04410-w
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genicular Artery Embolization Using Rapidly Resorbable Gelatin-based Microspheres for Osteoarthritis-related Knee Pain2026
  2. 2Genicular Artery Embolization (GAE) for the Treatment of Advanced Knee Osteoarthritis in Selected Nonoperative Patients: A Pilot Study at 6 Months Follow-Up2026
  3. 3Transarterial Embolization of Geniculate Arteries Reduces Pain and Improves Physical Function in Knee Osteoarthritis—A Prospective Cohort Study2024 · 14 citations
  4. 4Genicular Artery embolisation in Patients with Osteoarthritis of the Knee (GENESIS) Using Permanent Microspheres: Long-Term Results2024 · 27 citations
  5. 5Genicular Artery Embolization for Treatment of Symptomatic Knee Osteoarthritis: 2-Year Outcomes from a Prospective IDE Trial2024 · 6 citations