Demonstrates improved osteogenic differentiation in mesenchymal stem cells, suggesting a new approach for bone tissue engineering.
This study demonstrates that the combined use of vitamins D3 and K3, together with optimized dexamethasone exposure, provides a simple and biologically compatible strategy to improve the osteogenic differentiation of mesenchymal stem cells. This approach offers a physiologically relevant, safe, and cost-effective modification of standard osteogenic protocols and may contribute to the development of more efficient cell-based systems for bone tissue engineering and regenerative medicine.
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Dvořáková et al. (2026) studied this question.
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