Classifies malignant and immune cell states in pancreatic neuroendocrine tumors, suggesting new biomarkers for treatment.
This study provides a detailed single-nucleus transcriptomic classification of malignant, stromal, and immune cell types and states in PNETs, their interactions in the TME, and associations with clinical outcomes. The refined molecular taxonomy of PNET may guide the development of more efficacious biomarkers and therapeutic strategies.
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Qiu et al. (2026) studied this question.
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