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Elevated CD161+ Treg cells correlate with disease activity in Behçet Syndrome, suggesting their clinical relevance.
Patients with BS exhibit an increased CD161⁺ Treg cells in peripheral blood, which may contribute to immune dysregulation and neurologic involvement. The reduction of CD161⁺ Treg cells following treatment suggests their potential role as a biomarker for disease activity in BS.
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Li et al. (2026) studied this question.
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