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Analyzes metastability in Metropolis dynamics on hypercubes, suggesting implications for fitness landscapes.
Exact exponential-scale analysis of metastability for the single-bit Metropolis chain on the binary hypercube when the fitness function depends only on the Hamming weight (K=0 case). The chain projects onto a one-dimensional birth-death chain, enabling explicit computation of the rate function, critical threshold, and freezing-threshold asymptotics via series-resistance capacity theory and discrete Laplace methods. Three results are established: equilibrium delocalization under subextensive selection, sharp hitting-time asymptotics for smooth basins with an interior saddle (Regime I), and analogous results for piecewise-smooth basins with a boundary kink (Regime II). These K=0 formulas serve as the computation engine for the companion paper, which extends them to all NK landscapes with subextensive epistasis via Dirichlet form comparison.
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Hiroyuki Nashida (2026) studied this question.
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