Wait, scan and then? Exploring the long-term natural course of 119 low-grade central cartilaginous lesions of the long bones with MRI follow-up

Question Can specific MRI features help identify benign behavior in low-grade central cartilage lesions of long bones to support MRI-based surveillance? Findings Most low-grade lesions were stable or regressed (89%); increasing fat entrapment and/or fat replacement were associated with a benign natural course on MRI. Clinical relevance MRI features like fat entrapment and fat replacement support safe non-operative surveillance of LG-CCLs, avoiding unnecessary surgery.