Antimicrobial Photodynamic Therapy Using Chitosan-Encapsulated Indocyanine Green Improves Smear Layer Removal and Bond Strength to Caries-Affected Dentin: An In Vitro Study

Mohammed Hussain Dafer Al Wadei; Shan Sainudeen; Muhammad Qasim; Haifa Arsalan; Kashan Siddiqui; Madiha Pirvani

doi:10.1177/25785478261433608

March 18, 2026Photobiomodulation Photomedicine and Laser Surgery

Antimicrobial Photodynamic Therapy Using Chitosan-Encapsulated Indocyanine Green Improves Smear Layer Removal and Bond Strength to Caries-Affected Dentin: An In Vitro Study

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Key Points

This research aims to evaluate the effectiveness of chitosan-encapsulated indocyanine green in improving smear layer removal and bond strength in caries-affected dentin.
Applied antimicrobial photodynamic therapy using chitosan-encapsulated indocyanine green activated at 810 nm.
Compared the effects with conventional chlorhexidine (CHX) treatment.
Conducted in vitro experiments on caries-affected dentin.
Significant enhancement in smear layer removal compared to conventional CHX.
Improved resin-dentin bond strength observed with the chitosan-ICG system.

Implication

In vitro study shows that antimicrobial photodynamic therapy improves bond strength in dentin, indicating a novel approach for dental procedures.

Abstract

Near-infrared antimicrobial photodynamic therapy using chitosan-encapsulated ICG activated at 810 nm significantly enhanced both SL removal and resin-dentin bond strength compared with conventional CHX. The dual chelating and photosensitizing properties of the chitosan-ICG system offer a promising alternative for CAD surface conditioning before adhesive bonding.

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Cite This Study

Wadei et al. (2026) studied this question.

synapsesocial.com/papers/69be36f76e48c4981c6764b0 https://doi.org/10.1177/25785478261433608

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Antimicrobial Photodynamic Therapy Using Chitosan-Encapsulated Indocyanine Green Improves Smear Layer Removal and Bond Strength to Caries-Affected Dentin: An In Vitro Study

Key Points

Implication

Abstract

Discussion

Cite This Study

Antimicrobial Photodynamic Therapy Using Chitosan-Encapsulated Indocyanine Green Improves Smear Layer Removal and Bond Strength to Caries-Affected Dentin: An In Vitro Study

Key Points

Implication

Abstract

Discussion

Cite This Study

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