Demonstrates thickness changes in corneal epithelium due to altered salt concentrations, implying cellular adaptability.
When the salt concentration of the tear layer is reduced, the epithelium of the excised rabbit cornea begins to thicken within a few seconds. When the salt concentration is increased, the epithelium thins. After about six minutes a steady‐state is reached. It is shown that the epithelium can increase in thickness 50 per cent if the salt concentration is changed from 1.0% NaCl to 0.65% NaCl. Although this appears remarkable, it is a response which the epithelium shares with other living animal cells.
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Wilson et al. (1974) studied this question.
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