Meta-analysis finds oral cytology accurately detects oral epithelial dysplasia, suggesting reliable diagnostic potential.
This meta-analysis indicated that oral cytology exhibited high sensitivity and specificity in detecting oral epithelia dysplasia or worse, with slightly higher sensitivity for high-grade squamous intraepithelial lesion or worse. A notable advantage of using oral cytology with Papanicolaou staining is the potential for enhanced sensitivity.
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Chen et al. (2026) studied this question.
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