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March 21, 2026Journal of Neural Engineering1 citationsOpen Access

Multi-head noise regression for single-channel EEG: estimating ocular and muscle contamination to guide artifact removal

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USUsman Qamar ShaikhAKAnubha KalraALAndrew Lowe

Key Points

  • This research aims to develop a multi-head regression model to estimate ocular and muscle artifact contamination in EEG signals for selective artifact removal.
  • Developed a two-head regressor to estimate ocular (EOG) and muscle (EMG) noise-to-signal ratios from EEG data.
  • Synthesized single-channel EEG mixtures with known EOG/EMG contamination levels for training.
  • Evaluated model performance on independent datasets for validation in two applications: P3 ERP and RSVP P300 speller.
  • The dilated temporal convolutional network achieved a mean absolute error of approximately 1.8 dB for EOG and 1.0 dB for EMG.
  • Guided gating with the TCN preserved a high percentage of significant ERP channels compared to indiscriminate wavelet denoising.
  • Selective denoising improved area under the curve metrics in BCI applications, showing a significant increase in performance.

Abstract

EEG is often contaminated by ocular (EOG) and muscle (EMG) artifacts, yet many pipelines apply uniform denoising, risking distortion of clean neural activity. We propose a two-head, single-channel regressor that estimates EOG and EMG noise-to-signal ratio (NSR, dB) from short segments and test whether it can guide selective artifact reduction, including downstream BCI decoding. Approach. Using EEGdenoiseNet clean EEG and artifact exemplars, we synthesised 2-s single-channel mixtures with known EOG/EMG NSR spanning -10 to +10 dB and trained several model families to jointly regress both NSRs. Generalisation was evaluated on an independent eyeblink dataset via agreement with regression-based ocular-reference topographies, and in two applications: (i) gating stationary wavelet blink removal on a P3 ERP dataset and (ii) gating the same denoiser on a 55-subject RSVP P300 speller dataset (FP1/FP2). Main results. A dilated temporal convolutional network (TCN) performed best (EOG: MAE ≈ 1.8 dB, R² ≈ 0.82; EMG: MAE ≈ 1.0 dB, R² ≈ 0.94) with low bias across NSR. The EOG head recovered blink topographies (median spatial correlation ≈ 0.91). On the P3 dataset, indiscriminate wavelet denoising reduced significant ERP channels, whereas TCN-guided gating preserved 22-23 of 24 while processing ~9-20% of segments. On the speller dataset, denoising all epochs reduced decoding, while selective denoising improved AUC (θ = 9 dB: ΔAUC = 0.327, p = 0.0040) while denoising 12.45 ± 9.29% of test segments. Significance. Multi-head noise regression provides interpretable, continuous ocular and muscle contamination estimates that can act as control signals for conservative, noise-aware artifact handling under constrained-lead conditions. .

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Cite This Study

Shaikh et al. (2026) studied this question.

synapsesocial.com/papers/69be37406e48c4981c676b68https://doi.org/10.1088/1741-2552/ae541d
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