Analysis reveals herpesvirus genome integration in dementia patients, suggesting a link to specific conditions.
Over 7500 whole-genome sequences from controls and dementia patients were analyzed. Sequences consistent with integrated herpesviruses were identified using PathSeq. Prevalence of partial HHV-6 integration was higher in synucleinopathies. Herpesviruses genome integration may play a role in subsets of dementia patients.
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Piotrowski et al. (2026) studied this question.
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