This review demonstrates new applications of precision-cut lung slices in studying lung function and pathogenesis, indicating their significance for research.
Precision-cut lung slices (PCLS) is a modern approach used to study inter- and intracellular mechanisms in lungs , with minimal disruption to the overall cellular architecture of the tissue. The PCLS method has both advantages and disadvantages in comparison with other methods of studying lung cells. This review focused on contemporary research in lung cell biology, using the PCLS method. The objective is to emphasize new possibilities and potential applications of this method for studying the respiratory system under both normal and pathological conditions.
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Volozhinskaia et al. (2025) studied this question.
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