Molecular and physicochemical arrangement of chitosan–ibuprofen matrices for topical drug delivery on skin: preparation impact | Synapse
March 21, 2026Open Access
Molecular and physicochemical arrangement of chitosan–ibuprofen matrices for topical drug delivery on skin: preparation impact
Key Points
This research aims to explore the impact of the preparation process on chitosan-ibuprofen matrices for enhanced topical drug delivery.
Developed chitosan-ibuprofen matrices through various preparation techniques.
Evaluated physicochemical properties to determine their impact on drug release.
Conducted in vitro assessments of drug delivery efficiency on skin models.
Matrices exhibited altered physicochemical properties based on preparation methods.
Enhanced drug release rates were observed in optimized matrix formulations.
Demonstrated potential for improved patient-centric topical applications.
Abstract
Recent advances in modern medicine emphasize patient-centric and personalized therapeutic strategies, particularly for chronic and regenerative applications.