Total body irradiation (TBI) combining volumetric modulated arc therapy (VMAT) for thorax at standard source axis distance (SAD) with intensity modulated radiation therapy (IMRT) at extended SAD

Marc Delaperrière; Markus Hirt; Christian Felix Schulz; Frank André Siebert

doi:10.1002/acm2.70529

March 1, 2026Journal of Applied Clinical Medical PhysicsOpen Access

Total body irradiation (TBI) combining volumetric modulated arc therapy (VMAT) for thorax at standard source axis distance (SAD) with intensity modulated radiation therapy (IMRT) at extended SAD

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Key Points

The aim is to evaluate a new hybrid technique combining IMRT and VMAT for effective total body irradiation.
Developed a hybrid eSAD IMRT/VMAT technique for total body irradiation.
Focused on lung dose sparing during large-field irradiation.
Utilized standard and extended source axis distances in the treatment planning.
Demonstrated feasibility of the hybrid technique in clinical settings.
Achieved significant lung dose sparing compared to traditional methods.
Maintained robust coverage for large-field irradiation.

Implication

Study reveals a hybrid technique for lung dose sparing in total body irradiation, suggesting improved treatment options.

Abstract

This study showed the feasibility of a novel hybrid eSAD IMRT/VMAT TBI technique providing a clinically viable approach enabling effective lung dose sparing while maintaining the robustness of large-field irradiation.

Discussion

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Cite This Study

Delaperrière et al. (2026) studied this question.

synapsesocial.com/papers/69be38b56e48c4981c6794e8 https://doi.org/10.1002/acm2.70529

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Total body irradiation (TBI) combining volumetric modulated arc therapy (VMAT) for thorax at standard source axis distance (SAD) with intensity modulated radiation therapy (IMRT) at extended SAD

Key Points

Implication

Abstract

Discussion

Cite This Study

Total body irradiation (TBI) combining volumetric modulated arc therapy (VMAT) for thorax at standard source axis distance (SAD) with intensity modulated radiation therapy (IMRT) at extended SAD

Key Points

Implication

Abstract

Discussion

Cite This Study

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