A symmetric receive coil design for sentinel lymph node imaging

Magnetic Particle Imaging (MPI) based sentinel lymph node detection provides a novel technical approach for investigating lymphatic metastasis and therapeutic response in tumors. However, current MPI systems mainly employ global receive coils, which exhibit limited spatial specificity and low local sensitivity. In this study, a dedicated positioning platform and a symmetric surface receive coil were designed for localized MPI of the inguinal lymph node in mouse applications, enabling stable animal fixation and precise anatomical alignment. Experimental results demonstrated that the proposed design achieved high local sensitivity for magnetic particle signal detection.