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March 21, 2026Journal of Agricultural and Food Chemistry

Mechanistic Insights into Masked Fumonisin B1–Gliadin Complex Formation in Wheat

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Authors

HYHaoran YanYYYongli YeJJJian Ji

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Overview

Analysis elucidates fumonisin B1-gliadin binding in wheat, suggesting better mycotoxin detection methods.

Key Points

  • This research aims to explore the binding mechanism of fumonisin B1 with gliadin to better understand mycotoxin contamination.
  • Investigated noncovalent interactions between fumonisin B1 and gliadin.
  • Analyzed binding through static quenching mechanisms.
  • Characterized changes in protein secondary structure post-binding.
  • Fumonisin B1 binds to gliadin via hydrogen bonds, forming a stable complex.
  • Binding leads to increased α-helix and decreased β-sheet content in gliadin.
  • Binding occurs primarily within a hydrophobic pocket of gliadin.

Cite This Study

Yan et al. (2026) studied this question.

synapsesocial.com/papers/69be38ca6e48c4981c6795dehttps://doi.org/10.1021/acs.jafc.5c17494
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Structural and Mechanistic Insights into FgGWT1 as the Target of Aminopyrifen in <i>Fusarium graminearum</i> : from Binding Pockets Identification to Functional Validation2026
  2. 2Rapid Detection of Fumonisin B1 Using a Fluorescent Aptasensor with Plasmon-Modified Graphene Oxide as a Quencher2026
  3. 3The effects of the extrusion process used for the production of maize snacks and pasta on the free, bound, and total B fumonisin contents2024 · 2 citations
  4. 4GWA Study Identifies Two Positive Regulators of Mycotoxin Fumonisin B1 Tolerance in Arabidopsis2026
  5. 5Kinetics of Fumonisins B<sub>1</sub> and B<sub>2</sub>, Deoxynivalenol, and Deoxynivalenol-3-β-<scp>d</scp>-glucoside during Baking of Wheat–Maize Bread2025