Uncovers molecular profiles of germline variants in Chinese colorectal cancer, suggesting new research avenues.
Our study classified the clinicopathological features between sporadic CRC patients and LS patients. More importantly, the molecular profiling of the MMR gene germline variant was experimentally elucidated, which deepens the knowledge of MMR genes and provides a new perspective for the subsequent studies on the landscape of germline variants of Chinese LS patients.
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Zhu et al. (2026) studied this question.
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