This investigation explores benzylidene-substituted compounds inhibiting PIM-1 kinase in anticancer applications, suggesting new drug development pathways.
The results from this investigation revealed that benzylidene-substituted pyrazolo[3,4-b]pyridine derivatives are potential anticancer agents that could be developed as potential anticancer drug candidates by inhibiting PIM-1 kinase activity.
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Singh et al. (2026) studied this question.
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