Hydrogen Atom Transfer Enabled Acylsugars Synthesis via a Cooperative Copper and NHC Catalysis

Yuqiong Tan; Yu Xiang; Yang Ye

doi:10.1039/d6qo00128a

January 1, 2026Organic Chemistry Frontiers

Hydrogen Atom Transfer Enabled Acylsugars Synthesis via a Cooperative Copper and NHC Catalysis

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Key Points

To develop a direct acylation method for saccharides using dual catalysis.
Utilized a combination of copper and N-heterocyclic carbene (NHC) for catalysis.
Examined the modular Cu/NHC dual-catalysis system.
Focused on the tolerance and effectiveness of the acylation process.
Achieved successful acylation of saccharides.
Demonstrated excellent tolerance to various conditions.
Provided a modular and efficient method for synthesis.

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Implication

Direct acylation method for saccharides shows improved synthesis with copper and N-heterocyclic carbene catalysis, indicating excellent tolerance.

Abstract

In this study, we report a direct acylation method for saccharides, achieved through the combination of copper and N-heterocyclic carbene (NHC) catalysis. This modular Cu/NHC dual-catalysis system exhibits excellent tolerance...

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Cite This Study

Tan et al. (2026) studied this question.

synapsesocial.com/papers/69c08b6ba48f6b84677f8be7 https://doi.org/10.1039/d6qo00128a

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Hydrogen Atom Transfer Enabled Acylsugars Synthesis via a Cooperative Copper and NHC Catalysis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Hydrogen Atom Transfer Enabled Acylsugars Synthesis via a Cooperative Copper and NHC Catalysis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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