Preoperative Assessment in International Federation of Gynaecology and Obstetrics-2009 Stage IB2–IIB Cervical Cancer: Role of Delayed Gadolinium-Enhanced Magnetic Resonance Imaging After Neoadjuvant Chemotherapy

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Key Points

To evaluate the effectiveness of delayed Gadolinium-enhanced MRI versus standard T2/diffusion-weighted MRI for detecting residual tumor in cervical cancer post-chemotherapy.
Retrospective analysis of patients with FIGO stage IB2-IIB cervical cancer (2016-2020)
Neoadjuvant chemotherapy followed by radical hysterectomy and pelvic lymphadenectomy
Comparison of diagnostic accuracies between delayed Gadolinium-enhanced MRI and T2/diffusion-weighted MRI
Assessment of interobserver agreement using two radiologists
Delayed Gadolinium-enhanced MRI identified all 4 complete responders, compared to only 2 by T2/diffusion-weighted MRI
Significantly improved detection rates for lymph node metastases (84.5% versus 72.6%) with p < 0.0001
Improved diagnostic accuracy for parametrial invasion (97.6% versus 85.7%) and vaginal invasion (92.9% versus 80.9%)
Better interobserver agreement for vaginal invasion, parametrial invasion, and nodal status with delayed Gadolinium-enhanced MRI.

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Retrospective study assesses delayed Gadolinium-enhanced MRI's impact on cancer evaluation, suggesting improved diagnostic outcomes.

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Vandecaveye et al. (2026) studied this question.

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