In adults aged 50 and older, premature atrial contraction frequency is independently associated with age, height, cardiovascular history, natriuretic peptides, physical activity, and HDL cholesterol.
Supports hypothesis generation on PAC determinants; should not yet change practice in older adults.
To our knowledge, this is the first study to assess risk factors for PAC frequency in the general population aged ≥50 years. PACs are common, and their frequency is independently associated with age, height, history of cardiovascular disease, natriuretic peptide levels, physical activity, and high-density lipoprotein cholesterol. The underlying mechanisms of these relationships need to be addressed in future studies.
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Conen et al. (2012) studied this question.
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