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In adults aged 50 and older, premature atrial contraction frequency is independently associated with age, height, cardiovascular history, natriuretic peptides, physical activity, and HDL cholesterol.
To our knowledge, this is the first study to assess risk factors for PAC frequency in the general population aged ≥50 years. PACs are common, and their frequency is independently associated with age, height, history of cardiovascular disease, natriuretic peptide levels, physical activity, and high-density lipoprotein cholesterol. The underlying mechanisms of these relationships need to be addressed in future studies.
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Conen et al. (2012) studied this question.
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