This research demonstrates new therapeutic strategies to combat cisplatin resistance in small cell lung cancer, suggesting a pathway to personalized treatment.
Cisplatin resistance in SCLC is a complex, multifactorial process involving cellular, molecular, and microenvironmental mechanisms. Integrating mechanistic insights with emerging therapies, including immunotherapy, targeted therapy, and novel chemotherapeutics, offers a promising path to overcome resistance, guiding future research and the development of more effective, personalized treatment strategies for patients with cisplatin-resistant SCLC.
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Chen et al. (2026) studied this question.
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