Histone Acetyltransferase KAT14 Mediates CDH5 to Regulate Spiral Artery Remodeling in Preeclampsia via Cooperation With SRF

Key Points

• The study aims to understand the role of KAT14 in spiral artery remodeling and its implications for preeclampsia.
• Identification of KAT14 as an epigenetic regulator
• Analysis of its interaction with CDH5 and SRF
• Evaluation of remodeling effects on spiral arteries
• KAT14 is identified as crucial for regulating spiral artery remodeling
• Its role reveals new insights into preeclampsia pathogenesis
• KAT14 could serve as a potential therapeutic target