This research demonstrates direct amidation of alkynes, suggesting a new metal-free method for synthesis.
The conversion of alkynes into amides has largely relied on transition-metal catalysis, whereas metal-free approaches remain scarcely explored. Herein, we report a metal-free, direct amidation of alkynes using N-Boc-O-tosylhydroxylamine (TsONHBoc)...
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Divedi et al. (2026) studied this question.
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