December 9, 2004New England Journal of Medicine
Prophylactic Use of an Implantable Cardioverter–Defibrillator after Acute Myocardial Infarction
Why the study?
Does prophylactic ICD therapy reduce overall mortality in high-risk patients who have recently had a myocardial infarction?
Population
High-risk patients who have recently had a myocardial infarction
Authors
Discussion
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Member takes
Implication
Prophylactic ICDs early post-MI were not associated with lower mortality; leaves open optimal timing and selection for primary prevention.
Structured PICO
Does prophylactic ICD therapy reduce overall mortality in high-risk patients who have recently had a myocardial infarction?
P
Population
High-risk patients who have recently had a myocardial infarction
I
Intervention
Prophylactic implantable cardioverter-defibrillator (ICD) therapy
O
Outcome
Overall mortalityhard clinical
Prophylactic ICD implantation early after acute myocardial infarction does not improve overall survival due to an offsetting increase in nonarrhythmic deaths.
Cite This Study
Hohnloser et al. (2004) studied this question.