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March 26, 2026Urology Case Reports0 citationsOpen Access

Case Report: Metastatic pancreatic cancer to bilateral testes and spermatic cords

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MPMatthew PhillipiSRSidney C. RobertsDYDavid Yao

Key Points

  • To report a unique case of metastatic pancreatic cancer to the testes and spermatic cords.
  • Case evaluation of a 65-year-old male with a history of pancreatic cancer.
  • Assessment of groin pain and evaluation of testicular retraction.
  • Diagnosis confirmed through imaging and rising CA19-9 levels.
  • Palliative bilateral radical orchiectomy performed.
  • Metastatic pancreatic ductal adenocarcinoma identified in bilateral testes and spermatic cords.
  • First report of this metastatic condition documented in English literature.
  • Increased CA19-9 levels correlated with the metastatic progression.

Abstract

We present a 65-year-old man with pancreatic cancer treated with chemotherapy and chemoradiation for local control, who presented three years later with groin pain and a retracted right testis. Evaluation revealed pancreatic ductal adenocarcinoma metastatic to bilateral testes and spermatic cords with rising CA19-9. He underwent palliative bilateral radical orchiectomy. We present this case of metastatic pancreatic cancer to bilateral testes and spermatic cords as the first report in the English literature. This case highlights the need to consider metastatic disease in men over 40 presenting with a new testicular or spermatic cord mass and a history of malignancy.

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Cite This Study

Phillipi et al. (2026) studied this question.

synapsesocial.com/papers/69c4cc37fdc3bde4489177a7https://doi.org/10.1016/j.eucr.2026.103419
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rare Case of Testicular Metastasis of Prostate Carcinoma after 13 Years of Prostatectomy: A Case Report and Review of the Literature2024
  2. 2Unanticipated Testicular Involvement in Prostate Carcinoma: A Case Report2026
  3. 3Ascending colon cancer metastasized to the right testicle: a case report2024
  4. 4Simultaneous Metastatic Involvement of Bilateral Testes and Left Spermatic Cord in Prostate Cancer Detected on 68Ga-PSMA-11 PET/CT2024
  5. 5Painful penile erection as a manifestation of metastatic pancreatic ductal adenocarcinoma2026