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March 26, 2026IEEE Transactions on Computational Biology and Bioinformatics0 citations

Biomedical Named Entity Recognition and Relation Extraction: Methodologies, Challenges & Opportunities

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AGAndr´e Gonc¸alvesUniversidade do PortoHCHenrique Lopes CardosoUniversidade do PortoLRL. P. ReisUniversidade do Porto

Key Points

  • The manuscript aims to survey the evolution and methodologies of Biomedical Named Entity Recognition and Relation Extraction, along with their challenges and opportunities.
  • Comprehensive survey of existing methodologies for BioNER and BioRE.
  • Analysis of resources available for biomedical information extraction.
  • Discussion of challenges and opportunities in the field.
  • Identifies key methodologies in biomedical named entity recognition.
  • Highlights challenges faced in implementing information extraction techniques.
  • Discusses potential future directions for biomedical information extraction.

Abstract

With the volume of biomedical literature currently increasing at an unparalleled rate, researchers in biomedical sciences are quickly losing the capacity to single-handedly grasp the available information in a diversity of domains. However, owing to the growing body of available texts and open-access policies of an increasing number of publishers, Information Extraction (IE) in the biomedical domain is becoming an important task to aid in the condensation and systematization of scientific information in subject-specific areas and ideally reduce the burden of manual literature research in the biomedical scope. The present manuscript aims to provide a comprehensive survey on the tasks of Biomedical Named Entity Recognition (BioNER) and Biomedical Relation Extraction (BioRE), namely in terms of their evolution, current common methodologies, existing resources, and the challenges and opportunities they provide. Finally, a few possible routes for the development of Biomedical IE are also discussed.

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Cite This Study

Gonc¸alves et al. (2026) studied this question.

synapsesocial.com/papers/69c4cc69fdc3bde448917914https://doi.org/10.1109/tcbbio.2026.3676374
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