Retrospective study assesses GBS colonization and outcomes in pregnant women, suggesting improved screening strategies.
Key Points
The aim is to evaluate GBS colonization, detection methods, and antibiotic resistance in late pregnancy to enhance screening and reduce infection risk.
Retrospective analysis of pregnant women screened for GBS between 2017 and 2024.
Vaginal specimens tested using culture and qPCR methods.
Antibiotic susceptibility evaluation for culture-positive isolates.
Logistic regression analysis to identify risk factors for colonization.
Comparison of maternal and neonatal outcomes between colonized and non-colonized women.
Colonization rate was 3.9% by culture and 7.3% by qPCR among women tested.
qPCR showed significantly higher detection rates than culture methods.
High resistance observed for clindamycin (73.7%) and erythromycin (69.7%).
Colonized women experienced higher rates of premature rupture of membranes and chorioamnionitis.
Neonates of colonized women had increased odds of pathological jaundice and fetal distress.