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March 26, 2026Critical Care Medicine

761: Stop the Spread: Reducing Hospital-Acquired C Difficile Infections in a Community Icu

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Authors

KGKamalpreet GillHJHamna JavedACAndrew Clark

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Overview

Multidisciplinary QI initiative reduces ICU HA-CDI rates, indicating the importance of infection control measures.

Key Points

  • The aim is to reduce hospital-acquired Clostridioides difficile infections in the ICU through targeted interventions.
  • Plan-Do-Study-Act model implemented for year-long quality improvement project.
  • Enhanced environmental cleaning and UV disinfection practices were introduced.
  • Real-time feedback on hand hygiene and a hospital-wide advertising campaign for staff engagement.
  • Daily review of high-risk antibiotics to improve antibiotic stewardship.
  • Reinforced contact precautions with PPE education.
  • Hospital-wide CDI cases decreased slightly from 27 to 26 cases (↓3.7%).
  • ICU cases increased from 4 to 7 cases (↑75%) before targeted interventions began.
  • No ICU CDI cases reported from January to March 2025 after implementing interventions.
  • Hand hygiene compliance spiked to nearly 100% in October 2024.

Cite This Study

Gill et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccd6fdc3bde4489187cbhttps://doi.org/10.1097/01.ccm.0001185040.35587.05
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