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March 26, 2026European Heart Journal Acute Cardiovascular Care2 citations

Early clinical recovery in STEMI cardiogenic shock: insights from the DanGer shock trial

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RBRasmus Paulin BeskeAKAllan L. KleinLJLisette Okkels Jensen

Key Points

  • This research aims to identify factors associated with rapid recovery in patients with STEMI cardiogenic shock.
  • Analysis of patient outcomes from the DanGer Shock trial
  • Comparison of Fast Recovery patients to those without rapid recovery
  • Assessment of haemodynamic status, LVEF, age, and lactate levels
  • Fast Recovery patients exhibited higher LVEF and lower lactate levels
  • Approximately one-third of patients receiving standard care showed rapid recovery
  • Modest ability to predict rapid recovery based on initial characteristics

Abstract

The DanGer Shock trial showed a survival benefit of mAFP use in STEMI-CS, yet about one-third of SoC patients experienced rapid haemodynamic recovery. These 'Fast Recovery' patients were characterized by higher LVEF, younger age, and lower lactate, however discrimination between patients with and without rapid recovery was modest. Distinguishing patients who will recover rapidly remains challenging and warrants further investigation.

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Cite This Study

Beske et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccf7fdc3bde448918bbdhttps://doi.org/10.1093/ehjacc/zuag029
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