Introduction: Increased intracranial pressure (ICP) ≥ 20 mmHg is associated with poor neurologic outcomes in children with traumatic brain injury (TBI). Pupillometry measures pupil size, symmetry, and reactivity by stimulating pupillary constriction via light reflex. Neurologic pupillary index (nPI) is a derived measure of pupil constriction, latency, and velocity. Values range from 0 to 4.9, with abnormal being 3. Future research should examine a sample with higher prevalence of increase ICP to better elucidate its relationship with nPI.
Soto-Ruiz et al. (Sun,) studied this question.