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Analysis identifies distinct clinical-imaging phenotypes in MRI-negative temporal lobe epilepsy, suggesting improved diagnosis strategies.
These findings demonstrate that TLE-MRIneg represents a distinct clinical-imaging entity from TLE-HS. The identification of morphologically defined subtypes, particularly AE, highlights the heterogeneity of TLE-MRIneg and its potential clinical relevance. This work supports the use of advanced imaging and data-driven methods to improve diagnosis and guide individualized management in non-lesional epilepsies.
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Ballerini et al. (2026) studied this question.
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