One of the risk factors for the development and rupture of cerebral aneurysms is thought to be the temporal disturbance of wall shear stress (WSS) exerted by blood flow on the vessel wall. In previous hemodynamic studies, the average values for healthy adults were often used when setting the blood flow rate of the inflowing blood vessels as boundary conditions. However, in reality, blood flow rates vary significantly among individuals, and the impact of these variations on the temporal disturbances of WSS remains unclear. In this study, we conducted numerical simulations of blood flow under three different blood flow rate conditions for the actual vascular geometries of patients to investigate the extent to which blood flow rates influence simulation results. The results revealed that the dimensionless quantity NtransWSS, used to evaluate temporal disturbances in WSS, can be significantly influenced by blood flow rate depending on the vascular geometry. Therefore, to obtain more reliable results regarding temporal disturbances in WSS, it is considered necessary to use patient-specific data not only for vascular geometry but also for blood flow rate.
KINEBUCHI et al. (Wed,) studied this question.