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March 26, 2026AIDS0 citations

Male-specific association of HIV infection with lower risk of hyperuricemia is mediated by lower BMI and AGR

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TCTailin ChenGuangxi UniversityXCXiaoxiao ChenSWShanling Wang

Key Points

  • To examine the relationship between HIV infection and hyperuricemia in men and women, focusing on influencing factors.
  • Analyzed the prevalence of hyperuricemia in HIV-positive men and women.
  • Assessed body mass index (BMI) and albumin-to-globulin ratio (AGR) levels.
  • Compared metabolic profiles between genders.
  • Investigated mediation effects of BMI and AGR on hyperuricemia risk.
  • Men with HIV showed a significantly lower risk of hyperuricemia compared to women.
  • Lower BMI and AGR levels were found in HIV-positive men.
  • Metabolic profiles differ between male and female individuals with HIV, influencing hyperuricemia risk.

Abstract

HIV infection was associated with a lower risk of hyperuricemia in men but not women, partially mediated by lower BMI and AGR, suggesting distinct metabolic and inflammatory profiles in male PWH.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69c4cda5fdc3bde44891a499https://doi.org/10.1097/qad.0000000000004490
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