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Blood Hemoglobin Change During Maintenance Hemodialysis Sessions | Synapse

March 26, 2026

Blood Hemoglobin Change During Maintenance Hemodialysis Sessions

Key Points

This research focuses on understanding how blood hemoglobin levels change during maintenance hemodialysis sessions and the implications for anemia management.
Monitored blood hemoglobin (Hb) levels during maintenance hemodialysis sessions.
Analyzed the relationship between ultrafiltration volume/dry weight (UFV/DW) and hemoglobin changes.
Determined the thresholds for safe anemia therapy in patients based on UFV/DW.
Blood hemoglobin can increase by more than 20% when UFV/DW is greater than 0.05.
Typically, hemoglobin increases about 3% for every 1% increase in UFV/DW.
Anemia therapy should avoid raising pre-dialysis hemoglobin above 10.5 g/dL in patients requiring higher UFV/DW to minimize thrombotic risks.

Abstract

More than 20% increase in Hb can occur in sessions with UFV/DW > 0.05, whereas the typical increase is around 3% per 1% increase in UFV/DW. To reduce thrombotic risks, anemia therapy raising pre-dialysis Hb > 10.5 g/dL should preferably be avoided in MHD patients who require UFV/DW > 0.05.

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Cite This Study

Koiki et al. (Tue,) studied this question.

synapsesocial.com/papers/69c4cddcfdc3bde44891aa41 https://doi.org/https://doi.org/10.1111/sdi.70020

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