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March 27, 2026Chemical Communications2 citations

Accessing the less traveled path: Regioselective synthesis of 3-oxindoles

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TMTirtha MandalGCGargi ChakrabortiJDJyotirmayee Dash

Key Points

  • This research aims to explore methods for the regioselective synthesis of 3-oxindoles from indoxyls.
  • Utilized indoxyl as a precursor for synthesis
  • Employed regioselective synthetic pathways
  • Analyzed structural properties of synthesized compounds
  • Demonstrated successful synthesis of 3-oxindoles
  • Confirmed structural integrity through characterization techniques
  • Results indicate potential applications in bioactive molecule development

Abstract

Indoxyls, commonly known as 3-oxindoles, are privileged heterocyclic scaffolds found in natural products, bioactive molecules, and functional materials. Despite their close structural relationship to 2-oxindoles, selective access to 3-oxindoles, particularly...

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Cite This Study

Mandal et al. (2026) studied this question.

synapsesocial.com/papers/69c61fd715a0a509bde183e3https://doi.org/10.1039/d6cc00399k
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