Case report reveals dual impact of exercise-induced hypertension and high protein intake on renal health in a bodybuilder, suggesting serious implications for athletes.
High-protein diets and resistance training are widely practiced among athletes and bodybuilders. While moderate protein intake supports muscle growth, chronic excessive intake can lead to glomerular hyperfiltration and increased renal workload. Furthermore, transient but extreme surges in blood pressure during maximal resistance exercise may cause repeated microvascular injury. The synergistic impact of these factors on renal function remains poorly recognized. We report a case of end-stage kidney disease (ESKD) in a bodybuilder likely resulting from the combined effects of exercise-induced hypertension and sustained high protein intake.
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Tamura et al. (2026) studied this question.
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