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March 27, 2026Chemical Communications5 citations

When Mechanochemistry Meets Fluorine

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VPVishal B. PurohitRPRonak V. PrajapatiVPVaibhav D. Prajapati

Key Points

  • This research aims to enhance the synthesis of fluoro and fluorinated compounds using mechanochemistry. It seeks to elucidate the effectiveness and efficiency of these synthetic approaches.
  • Analyzed various mechanochemical techniques for fluorination.
  • Compared traditional synthesis methods with mechanochemical methods.
  • Investigated the application of these techniques in producing intact organofluorine compounds.
  • Mechanochemical methods demonstrated higher efficiency in fluorination compared to traditional methods.
  • Enhanced reaction times and yields were observed with mechanochemical approaches.
  • The techniques showed potential for broad applications in pharmaceuticals and agrochemicals.

Abstract

Given the importance of organofluorine compounds as potent pharmaceuticals, agrochemicals, and fine chemicals, there has been a surge in synthetic approaches to introduce fluoro/fluorinated functionality into intact molecules. Among them,...

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Cite This Study

Purohit et al. (2026) studied this question.

synapsesocial.com/papers/69c6206115a0a509bde18e59https://doi.org/10.1039/d6cc01414c
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