This series synthesizes predictions regarding the nervous system's structural framework, indicating new avenues for experimental validation.
This paper closes the IMH series. It does not introduce new theoretical machinery. Its purpose is architectural: to lay out the complete structure that the eight papers have built, to state explicitly what the series claims and what it does not claim, to enumerate the 59 falsifiable predictions distributed across Papers~0 through~7, and to identify the experimental programme that would confirm or refute the framework. The IMH series proposes that the nervous system is a hierarchy of ionic-mechano-hydraulic gel systems operating on five spatial scales and five temporal decades, regulated by a distributed fluidic supervisor whose physical state vector P⃗ = ₀,\, β,\, σcrit,\, σbody,\, ∇⃗σ\ constitutes both the substrate of physiological regulation and the physical basis of conscious experience. This supervisor is not a metaphor and not a functional abstraction. It is a material entity — a viscoelastic gel distributed across the enteric, spinal, and central nervous system — whose parameters are measurable by existing technologies and whose behaviour is governed by the same physics as any soft-matter system subjected to periodic stress. The series does not claim to have measured this entity. It claims to have identified it, to have specified its parameters and to have derived from those parameters 59 predictions that are falsifiable by methods currently available or near-available: magnetic resonance elastography, diffusion-weighted magnetic resonance imaging, periaxonal optical coherence tomography, autonomic psychophysiology, pharmacological gel manipulation, and controlled sensory deprivation. The closing statement of the series is this: the supervisor is the matter that remains to be discovered in the living.
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Delalande et al. (2026) studied this question.
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