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Successful Treatment of Acquired Idiopathic Generalized Anhidrosis With Baricitinib | Synapse

March 27, 2026

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Successful Treatment of Acquired Idiopathic Generalized Anhidrosis With Baricitinib

Puntos clave

To report the effectiveness of baricitinib in treating acquired idiopathic generalized anhidrosis in patients.
Described two cases of patients with acquired idiopathic generalized anhidrosis.
Administered baricitinib for treatment.
Both patients showed improvement in symptoms after treatment with baricitinib.

Resumen

This case report describes 2 otherwise healthy patients who presented with acquired idiopathic generalized anhidrosis and were treated with baricitinib.

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Cite This Study

Chang et al. (Wed,) studied this question.

synapsesocial.com/papers/69c620d515a0a509bde197ff https://doi.org/https://doi.org/10.1001/jamadermatol.2026.0010

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis2020 · 279 citations
2Revised guideline for the diagnosis and treatment of acquired idiopathic generalized anhidrosis in Japan2016 · 83 citations
3JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies2018 · 527 citations
4Acquired Idiopathic Generalized Anhidrosis and Frontal Fibrosing Alopecia: Possible Evidence for a Shared Autoimmune Pathogenesis2025 · 1 citations
5Multiple courses of steroid pulse therapy are required in treating acquired idiopathic generalized anhidrosis patients with a large anhidrotic area: A retrospective study of 28 cases2023 · 3 citations