Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long-term outcome

Sara A. Jablonski Wennogle; Yue Xiang Chen; Jarod E. Williams; Jessica A. Kendziorski; Rebecca C. Smedley

doi:10.1111/jvim.16922

November 3, 2023SHILAP Revista de lepidopterologíaOpen Access

Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long-term outcome

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Key Points

To evaluate the prevalence, clinical predictors, and prognostic significance of concurrent liver pathology in dogs diagnosed with gallbladder mucocele.
Assessed histologic liver abnormalities and portal fibrosis scores in dogs diagnosed with gallbladder mucocele.
Analyzed the relationship between systemic inflammatory markers, specifically neutrophil-to-lymphocyte ratio, and post-cholecystectomy outcomes.
Histologic liver abnormalities occur commonly in dogs affected by gallbladder mucocele.
Higher portal fibrosis scores associate with reduced long-term survival following cholecystectomy.
Elevated neutrophil-to-lymphocyte ratios predict the presence of hepatic necrosis and cholangitis or cholangiohepatitis.

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Implication

Observational study shows liver fibrosis impairs post-cholecystectomy survival in dogs with gallbladder mucocele, highlighting the prognostic value of concurrent hepatopathy.

Abstract

Histologic abnormalities of the liver are common in dogs with GBM. A higher portal fibrosis score might be associated with shortened long-term survival after cholecystectomy for dogs with GBM. An increase in NLR might predict hepatic necrosis and cholangitis/cholangiohepatitis in dogs with GBM.

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Wennogle et al. (2023) studied this question.

synapsesocial.com/papers/69c6e23e724f27ce0c0d98f4 https://doi.org/10.1111/jvim.16922

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Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long-term outcome

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long-term outcome

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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