Key result
Simultaneous TAVR and liver transplantation demonstrates procedural feasibility in severe aortic stenosis and decompensated cirrhosis.
Why the study?
Managing concomitant severe AS and cirrhosis is challenging, and evidence on whether TAVR combined with liver transplantation is feasible in these high-risk patients is limited.
Simultaneous TAVR and liver transplantation is feasible in selected high-risk patients with severe aortic stenosis and decompensated cirrhosis.
Hypothesis-generating for simultaneous TAVR-liver transplant in decompensated cirrhosis; prospective trials needed before clinical adoption.
Managing patients with concomitant severe aortic stenosis (AS) and cirrhosis presents significant clinical challenges due to the complex interplay between cardiac and hepatic dysfunction. Emerging evidence suggests that transcatheter aortic valve replacement (TAVR) may be a safe and effective intervention in cirrhotic patients with severe AS, potentially serving as a bridge to restore transplant candidacy. We report two cases of decompensated cirrhotic patients who successfully underwent simultaneous TAVR and liver transplantation (LT). These cases illustrate the feasibility of combined cardiac and hepatic procedures in selected high-risk patients. However, such interventions require meticulous preoperative evaluation, multidisciplinary coordination, and institutional expertise.
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Chavarriaga et al. (2026) studied this question. Simultaneous TAVR and liver transplantation was successfully performed in two patients with severe aortic stenosis and decompensated cirrhosis, demonstrating procedural feasibility.
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