What question did this study set out to answer?

The research aims to evaluate the effectiveness of thoracic paravertebral block in enhancing pain control and spinal alignment post-vertebroplasty.

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March 28, 2026Open Access

Effectiveness of Thoracic Paravertebral Block in Minimally Invasive Vertebroplasty: A Retrospective Cohort Study Focusing on Pain Trajectories and Sagittal Spinal Alignment

Key Points

The research aims to evaluate the effectiveness of thoracic paravertebral block in enhancing pain control and spinal alignment post-vertebroplasty.
Conducted a retrospective cohort analysis of patients undergoing minimally invasive vertebroplasty
Evaluated postoperative pain trajectories and opioid consumption
Assessed sagittal spinal alignment changes post-procedure
Postoperative pain significantly reduced in patients receiving thoracic paravertebral block
Opioid consumption was lower in the TPVB group
Sagittal spinal alignment improved after the procedure with TPVB

Abstract

Ultrasound-guided TPVB combined with GA significantly improves postoperative pain trajectories, reduces opioid consumption, and enhances sagittal spinal alignment in MIVP patients. TPVB may modulate nociceptive and neuroinflammatory pathways, offering a safer analgesic option for spinal surgery in osteoporotic patients. Prospective randomized trials are warranted to confirm these findings.

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