What question did this study set out to answer?

The aim is to evaluate the incidence of sleep and psychiatric disturbances in patients with nephrotic syndrome after starting corticosteroid therapy.

March 28, 2026Open Access

Wcn26-8401 Incidence of Sleep and Psychiatric Disturbances in Patients of Nephrotic Syndrome Aged ≥13 Years After Initiation of Corticosteroid Therapy

Puntos clave

The aim is to evaluate the incidence of sleep and psychiatric disturbances in patients with nephrotic syndrome after starting corticosteroid therapy.
Analyzed patient outcomes post-initiation of corticosteroid treatment
Monitored incidence of psychiatric and sleep disturbances
Considered comparative effectiveness of tacrolimus and cyclosporine
Tacrolimus showed similar or higher remission rates compared to cyclosporine
Fewer total reported adverse events were associated with tacrolimus
Data quality was inconsistent, necessitating further research

Resumen

Conclusion:Current evidence indicates that tacrolimus may achieve comparable or higher remission rates than cyclosporine, with fewer total reported adverse events.However, the available data are limited by small sample sizes, heterogeneous study designs, and variable reporting quality, with inconsistent statistical significance.Robust, adequately powered randomized controlled trials are needed to establish the true comparative efficacy and safety of these agents.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

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